Cystic Fibrosis Transmembrane Conductance Regulator (CFTR) Ubiquitylation as a Novel Pharmaceutical Target for Cystic Fibrosis
Mutations in the cystic fibrosis transmembrane conductance regulator (<i>CFTR)</i> gene decrease the structural stability and function of the CFTR protein, resulting in cystic fibrosis. Recently, the effect of CFTR-targeting combination therapy has dramatically increased, and it is expec...
Main Authors: | , |
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Format: | Article |
Language: | English |
Published: |
MDPI AG
2020-04-01
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Series: | Pharmaceuticals |
Subjects: | |
Online Access: | https://www.mdpi.com/1424-8247/13/4/75 |