Easy-Prime: a machine learning–based prime editor design tool

Abstract Prime editing is a revolutionary genome-editing technology that can make a wide range of precise edits in DNA. However, designing highly efficient prime editors (PEs) remains challenging. We develop Easy-Prime, a machine learning–based program trained with multiple published data sources. E...

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Bibliographic Details
Main Authors: Yichao Li, Jingjing Chen, Shengdar Q. Tsai, Yong Cheng
Format: Article
Language:English
Published: BMC 2021-08-01
Series:Genome Biology
Subjects:
Online Access:https://doi.org/10.1186/s13059-021-02458-0