Aspartic Acid Isomerization Characterized by High Definition Mass Spectrometry Significantly Alters the Bioactivity of a Novel Toxin from <i>Poecilotheria</i>

Research in toxinology has created a pharmacological paradox. With an estimated 220,000 venomous animals worldwide, the study of peptidyl toxins provides a vast number of effector molecules. However, due to the complexity of the protein-protein interactions, there are fewer than ten venom-derived mo...

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Bibliographic Details
Main Authors: Stephen R. Johnson, Hillary G. Rikli
Format: Article
Language:English
Published: MDPI AG 2020-03-01
Series:Toxins
Subjects:
Online Access:https://www.mdpi.com/2072-6651/12/4/207