APOL1 Risk Alleles Are Associated With More Severe Arteriosclerosis in Renal Resistance Vessels With Aging and Hypertension

APOL1 Risk Alleles Are Associated With More Severe Arteriosclerosis in Renal Resistance Vessels With Aging and Hypertension

The increased risk of end-stage kidney disease among hypertensive African Americans is partly related to APOL1 allele variants. The initial glomerulosclerosis of hypertension-associated arterionephrosclerosis consists of focal global glomerulosclerosis, but in biopsy studies, focal segmental glomeru...

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Bibliographic Details
Main Authors: Michael D. Hughson, Wendy E. Hoy, Susan A. Mott, Victor G. Puelles, John F. Bertram, Cheryl A. Winkler, Jeffrey B. Kopp
Format: Article
Language:English
Published: Elsevier 2016-05-01
Series:Kidney International Reports
Subjects:
aging
APOL1 variants
arteriosclerosis
hypertension
race
Online Access:http://www.sciencedirect.com/science/article/pii/S2468024916300018

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http://www.sciencedirect.com/science/article/pii/S2468024916300018

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