Formaldehyde-Induced Shrinkage of Rat Thymocytes

To test the possibility that micromolar formaldehyde, a metabolite of methanol derived from aspartame, exerts cytotoxicity, its effect on rat thymocytes was examined under the in vitro condition using a flow cytometer. Incubation of thymocytes with formaldehyde at 100 μM or more for 24 h significant...

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Bibliographic Details
Main Authors: Hiromi Nakao, Chisato Umebayashi, Mami Nakata, Yasutaka Nishizaki, Katuhiko Noda, Yasuo Oyama
Format: Article
Language:English
Published: Elsevier 2003-01-01
Series:Journal of Pharmacological Sciences
Online Access:http://www.sciencedirect.com/science/article/pii/S1347861319327793