Systematic Comparison of Hospital-Wide Standard and Model-Based Therapeutic Drug Monitoring of Vancomycin in Adults

Systematic Comparison of Hospital-Wide Standard and Model-Based Therapeutic Drug Monitoring of Vancomycin in Adults

We aimed to evaluate the predictive performance and predicted doses of a single-model approach or several multi-model approaches compared with the standard therapeutic drug monitoring (TDM)-based vancomycin dosing. We performed a hospital-wide monocentric retrospective study in adult patients treate...

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Bibliographic Details
Main Authors: Heleen Gastmans, Erwin Dreesen, Sebastian G. Wicha, Nada Dia, Ellen Spreuwers, Annabel Dompas, Karel Allegaert, Stefanie Desmet, Katrien Lagrou, Willy E. Peetermans, Yves Debaveye, Isabel Spriet, Matthias Gijsen
Format: Article
Language:English
Published: MDPI AG 2022-07-01
Series:Pharmaceutics
Subjects:
vancomycin
therapeutic drug monitoring
population pharmacokinetics
precision dosing
predictive performance
model averaging
Online Access:https://www.mdpi.com/1999-4923/14/7/1459

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https://www.mdpi.com/1999-4923/14/7/1459

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