First Exon Length Controls Active Chromatin Signatures and Transcription

First Exon Length Controls Active Chromatin Signatures and Transcription

Here, we explore the role of splicing in transcription, employing both genome-wide analysis of human ChIP-seq data and experimental manipulation of exon-intron organization in transgenic cell lines. We show that the activating histone modifications H3K4me3 and H3K9ac map specifically to first exon-i...

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Bibliographic Details
Main Authors: Nicole I. Bieberstein, Fernando Carrillo Oesterreich, Korinna Straube, Karla M. Neugebauer
Format: Article
Language:English
Published: Elsevier 2012-07-01
Series:Cell Reports
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124712001581

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http://www.sciencedirect.com/science/article/pii/S2211124712001581

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