Multivariate profiling of neurodegeneration-associated changes in a subcellular compartment of neurons via image processing

<p>Abstract</p> <p>Background</p> <p>Dysfunction in the endolysosome, a late endosomal to lysosomal degradative intracellular compartment, is an early hallmark of some neurodegenerative diseases, in particular Alzheimer's disease. However, the subtle morphological...

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Bibliographic Details
Main Authors: Kumarasamy Saravana K, Wang Yunshi, Viswanathan Vignesh, Kraut Rachel S
Format: Article
Language:English
Published: BMC 2008-11-01
Series:BioData Mining
Online Access:http://www.biodatamining.org/content/1/1/10