Disruption of the HLA-E/NKG2X axis is associated with uncontrolled HIV infections

Disruption of the HLA-E/NKG2X axis is associated with uncontrolled HIV infections

The contribution of the HLA-E/NKG2X axis in NK-mediated control of HIV infection remains unclear. We have studied the relationship between HLA-E expression and phenotypical as well as functional characteristics of NK cells, in the context of chronic HIV infection and in an in vitro model of acute in...

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Bibliographic Details
Main Authors: Luis Romero-Martín, Clara Duran-Castells, Mireia Olivella, Míriam Rosás-Umbert, Marta Ruiz-Riol, Jorge Sanchez, Dennis Hartigan-O´Connor, Beatriz Mothe, Àlex Olvera, Christian Brander
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-11-01
Series:Frontiers in Immunology
Subjects:
HIV
Natural Killer cells
HLA-E
NKG2A
NKG2C
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2022.1027855/full

Internet

https://www.frontiersin.org/articles/10.3389/fimmu.2022.1027855/full

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