Recent Advances in Lung Cancer Immunotherapy: Input of T-Cell Epitopes Associated With Impaired Peptide Processing

Recent Advances in Lung Cancer Immunotherapy: Input of T-Cell Epitopes Associated With Impaired Peptide Processing

Recent advances in lung cancer treatment are emerging from new immunotherapies that target T-cell inhibitory receptors, such as programmed cell death-1 (PD-1). However, responses to anti-PD-1 antibodies as single agents are observed in fewer than 20% of non-small-cell lung cancer (NSCLC) patients, a...

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Bibliographic Details
Main Authors: Marine Leclerc, Laura Mezquita, Guillaume Guillebot De Nerville, Isabelle Tihy, Ines Malenica, Salem Chouaib, Fathia Mami-Chouaib
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-07-01
Series:Frontiers in Immunology
Subjects:
lung cancer
cancer immunotherapy
cancer vaccine
tumor escape
antigen presentation and processing
T-cell epitope associated with impaired peptide processing
Online Access:https://www.frontiersin.org/article/10.3389/fimmu.2019.01505/full

Internet

https://www.frontiersin.org/article/10.3389/fimmu.2019.01505/full

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