A diverse ancestrally-matched reference panel increases genotype imputation accuracy in a underrepresented population
Abstract Variant imputation, a common practice in genome-wide association studies, relies on reference panels to infer unobserved genotypes. Multiple public reference panels are currently available with variations in size, sequencing depth, and represented populations. Currently, limited data exist...
| Huvudupphovsmän: | , , , , , , , , , |
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| Materialtyp: | Artikel |
| Språk: | English |
| Publicerad: |
Nature Portfolio
2023-07-01
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| Serie: | Scientific Reports |
| Länkar: | https://doi.org/10.1038/s41598-023-39429-3 |