The omega-3 polyunsaturated fatty acid docosahexaenoic acid inhibits proliferation and progression of non-small cell lung cancer cells through the reactive oxygen species-mediated inactivation of the PI3K /Akt pathway

The omega-3 polyunsaturated fatty acid docosahexaenoic acid inhibits proliferation and progression of non-small cell lung cancer cells through the reactive oxygen species-mediated inactivation of the PI3K /Akt pathway

Abstract Background Docosahexaenoic acid(DHA) inhibits tumor growth and progression in various cancers, including lung cancer. However, the mechanisms involved remain unclear. The aim of this study was to identify the mechanism of DHA in inhibiting progression of non-small cell lung cancer (NSCLC) i...

Full description

Bibliographic Details
Main Authors: Yuanqin Yin, Chengguang Sui, Fandong Meng, Ping Ma, Youhong Jiang
Format: Article
Language:English
Published: BMC 2017-05-01
Series:Lipids in Health and Disease
Subjects:
Lung cancer
Proliferation
Migration
Invasion
Reactive oxygen species
Online Access:http://link.springer.com/article/10.1186/s12944-017-0474-x

Internet

http://link.springer.com/article/10.1186/s12944-017-0474-x

Similar Items