Atroposelective desymmetrization of 2-arylresorcinols via Tsuji-Trost allylation
Desymmetrization of symmetric biaryls is an efficient but underexplored way to approach axially chiral molecules. Here, the authors report the atroposelective desymmetrization of 2- arylresorcinols via chiral palladium complex-catalyzed allylic alkylation.
| Main Authors: | , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Nature Portfolio
2023-02-01
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| Series: | Communications Chemistry |
| Online Access: | https://doi.org/10.1038/s42004-023-00839-z |