Pyrenebutyrate Pt(IV) Complexes with Nanomolar Anticancer Activity

Pyrenebutyrate Pt(IV) Complexes with Nanomolar Anticancer Activity

Research on platinum-based anticancer drugs continuously strives to develop new non-classical platinum complexes. Pt(IV) prodrugs are the most promising, and their activation-by-reduction mechanism of action is being explored as a prospect for higher selectivity and efficiency. Herein, we present th...

Full description

Bibliographic Details
Main Authors: Anife Ahmedova, Rositsa Mihaylova, Silviya Stoykova, Veronika Mihaylova, Nikola Burdzhiev, Viktoria Elincheva, Georgi Momekov, Denitsa Momekova
Format: Article
Language:English
Published: MDPI AG 2023-09-01
Series:Pharmaceutics
Subjects:
platinum(IV) prodrugs
anticancer agents
cytotoxicity
cellular uptake
activation by reduction
Online Access:https://www.mdpi.com/1999-4923/15/9/2310

Internet

https://www.mdpi.com/1999-4923/15/9/2310

Similar Items