Effect of mechanical insufflation-exsufflation for ineffective cough on weaning duration in diseases of the peripheral or central nervous system (MEDINE): study protocol for a randomised controlled trial in a neurological weaning centre

Introduction Patients with neurological or neurosurgical disease can suffer from impaired cough, which may result in life-threatening retention of tracheobronchial secretions, atelectasis, pneumonia and finally death. Due to a lack of alternatives and pathophysiological plausibility, the application...

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Bibliographic Details
Main Authors: Alexander Seipp, Antje Timmer, Andreas Klausen, Teresa Grimm, Martin Groß, Oliver Summ, Fabian Otto-Sobotka
Format: Article
Language:English
Published: BMJ Publishing Group 2023-07-01
Series:BMJ Open
Online Access:https://bmjopen.bmj.com/content/13/7/e071273.full