Using the longest significance run to estimate region-specific p-values in genetic association mapping studies

<p>Abstract</p> <p>Background</p> <p>Association testing is a powerful tool for identifying disease susceptibility genes underlying complex diseases. Technological advances have yielded a dramatic increase in the density of available genetic markers, necessitating an in...

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Bibliographic Details
Main Authors: Yang Hsin-Chou, Lin Ying-Chao, Lin Yi-Hsien, Lian Ie-Bin, Chang Chee-Jang, Fann Cathy SJ
Format: Article
Language:English
Published: BMC 2008-05-01
Series:BMC Bioinformatics
Online Access:http://www.biomedcentral.com/1471-2105/9/246