Periodic static compression of micro-strain pattern regulates endochondral bone formation

Introduction: Developmental engineering based on endochondral ossification has been proposed as a potential strategy for repairing of critical bone defects. Bone development is driven by growth plate-mediated endochondral ossification. Under physiological conditions, growth plate chondrocytes underg...

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Bibliographic Details
Main Authors: Pengzhen Cheng, Xueyi Zhao, Meige Han, Yaping Zhuang, Fenru Ning, Yaqian Hu, Weiguang Lu, Sheng Miao, Chengxiang Zhao, Liyuan Jia, Xue Hao, Meng Sun, Junxiang Wang, Fulin Chen, Liu Yang, Qiang Jie
Format: Article
Language:English
Published: Frontiers Media S.A. 2024-03-01
Series:Frontiers in Bioengineering and Biotechnology
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fbioe.2024.1356135/full