Metabolic Changes during In Vivo Maturation of PSC-Derived Skeletal Myogenic Progenitors

Metabolic Changes during In Vivo Maturation of PSC-Derived Skeletal Myogenic Progenitors

In vitro-generated pluripotent stem cell (PSC)-derived Pax3-induced (iPax3) myogenic progenitors display an embryonic transcriptional signature, but upon engraftment, the profile of re-isolated iPax3 donor-derived satellite cells changes toward similarity with postnatal satellite cells, suggesting t...

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Bibliographic Details
Main Authors: Phablo Abreu, Bayardo I. Garay, Travis Nemkov, Aline M. S. Yamashita, Rita C. R. Perlingeiro
Format: Article
Language:English
Published: MDPI AG 2023-12-01
Series:Cells
Subjects:
pluripotent stem cells
myogenic progenitors
metabolism
in vitro
in vivo
satellite cells
Online Access:https://www.mdpi.com/2073-4409/13/1/76

Internet

https://www.mdpi.com/2073-4409/13/1/76

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