Comprehensive Genetic Analysis of DGAT2 Mutations and Gene Expression Patterns in Human Cancers

Comprehensive Genetic Analysis of DGAT2 Mutations and Gene Expression Patterns in Human Cancers

DGAT2 is a transmembrane protein encoded by the DGAT2 gene that functions in lipid metabolism, triacylglycerol synthesis, and lipid droplet regulation. Cancer cells exhibit altered lipid metabolism and mutations in DGAT2 may contribute to this state. Using data from the Catalogue of Somatic Mutation...

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Bibliographic Details
Main Authors: Meghan Graber, Hayley Barta, Ryan Wood, Amrit Pappula, Martin Vo, Ruben C. Petreaca, Wilber Escorcia
Format: Article
Language:English
Published: MDPI AG 2021-07-01
Series:Biology
Subjects:
lipid metabolism
lipid droplet
lipid storage
DNA damage
mutation
gene expression
Online Access:https://www.mdpi.com/2079-7737/10/8/714

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https://www.mdpi.com/2079-7737/10/8/714

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