Histone Citrullination Mediates a Protective Role in Endothelium and Modulates Inflammation

Histone Citrullination Mediates a Protective Role in Endothelium and Modulates Inflammation

NETosis is a key host immune process against a pathogenic infection during innate immune activation, consisting of a neutrophil “explosion” and, consequently, NET formation, containing mainly DNA, histones, and other nuclear proteins. During sepsis, an exacerbated immune host response to an infectio...

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Bibliographic Details
Main Authors: Rebeca Osca-Verdegal, Jesús Beltrán-García, Ana B. Paes, Elena Nacher-Sendra, Susana Novella, Carlos Hermenegildo, Nieves Carbonell, José Luis García-Giménez, Federico V. Pallardó
Format: Article
Language:English
Published: MDPI AG 2022-12-01
Series:Cells
Subjects:
citrullination
histones
NETosis
sepsis
septic shock
progression
Online Access:https://www.mdpi.com/2073-4409/11/24/4070

Internet

https://www.mdpi.com/2073-4409/11/24/4070

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