Circulating pyruvate is a potent prognostic marker for critical COVID-19 outcomes

Circulating pyruvate is a potent prognostic marker for critical COVID-19 outcomes

BackgroundCoronavirus-19 (COVID-19) disease is driven by an unchecked immune response to the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) virus which alters host mitochondrial-associated mechanisms. Compromised mitochondrial health results in abnormal reprogramming of glucose metabol...

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Bibliographic Details
Main Authors: Victòria Ceperuelo-Mallafré, Laia Reverté, Joaquim Peraire, Ana Madeira, Elsa Maymó-Masip, Miguel López-Dupla, Alicia Gutierrez-Valencia, Ezequiel Ruiz-Mateos, Maria José Buzón, Rosa Jorba, Joan Vendrell, Teresa Auguet, Montserrat Olona, Francesc Vidal, Anna Rull, Sonia Fernández-Veledo
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-09-01
Series:Frontiers in Immunology
Subjects:
COVID-19
energy-related metabolites
fluorometric quantification
pyruvate
semi-targeted metebolomics
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2022.912579/full

Internet

https://www.frontiersin.org/articles/10.3389/fimmu.2022.912579/full

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