WNK3 promotes the invasiveness of glioma cell lines under hypoxia by inducing the epithelial-to-mesenchymal transition

The primary features of malignant glioma include high rates of mortality and recurrence, uncontrollable invasiveness, strong angiogenesis, and widespread hypoxia. The hypoxic microenvironment is an important factor affecting the malignant progression of glioma. However, the molecular mechanisms unde...

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Bibliographic Details
Main Authors: Wang Yue, Wu Bingbing, Long Shengrong, QiangLiu, Li Guangyu
Format: Article
Language:English
Published: De Gruyter 2021-08-01
Series:Translational Neuroscience
Subjects:
Online Access:https://doi.org/10.1515/tnsci-2020-0180