The role of OFD1 in selective autophagy

Autophagy is a cellular self-degradative pathway. Our study unveiled a novel mechanism mediated by OFD1, the protein mutated in Oral-Facial-Digital type I syndrome, based on selective degradation of autophagic proteins, which enables cells to calibrate their self-degradation. We demonstrated that un...

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Bibliographic Details
Main Authors: Brunella Franco, Manuela Morleo
Format: Article
Language:English
Published: Taylor & Francis Group 2021-05-01
Series:Molecular & Cellular Oncology
Subjects:
Online Access:http://dx.doi.org/10.1080/23723556.2021.1903291