A Thermal and Enzymatic Dual‐Stimuli Responsive DNA‐Based Nanomachine for Controlled mRNA Delivery

A Thermal and Enzymatic Dual‐Stimuli Responsive DNA‐Based Nanomachine for Controlled mRNA Delivery

Abstract The extreme instability of mRNA makes the practical application of mRNA‐based vaccines heavily rely on efficient delivery system and cold chain transportation. Herein, a DNA‐based nanomachine, which achieves programmed capture, long‐term storage without cryopreservation, and efficient deliv...

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Bibliographic Details
Main Authors: Feng Li, Xiaolei Sun, Jing Yang, Jin Ren, Mengxue Huang, Shengqi Wang, Dayong Yang
Format: Article
Language:English
Published: Wiley 2023-02-01
Series:Advanced Science
Subjects:
DNA nanotechnology
mRNA delivery
nanomedicine
self‐assembly
Online Access:https://doi.org/10.1002/advs.202204905

Internet

https://doi.org/10.1002/advs.202204905

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