Site Selectivity in Pd-Catalyzed Reactions of α-Diazo-α-(methoxycarbonyl)acetamides: Effects of Catalysts and Substrate Substitution in the Synthesis of Oxindoles and β-Lactams

Site Selectivity in Pd-Catalyzed Reactions of α-Diazo-α-(methoxycarbonyl)acetamides: Effects of Catalysts and Substrate Substitution in the Synthesis of Oxindoles and β-Lactams

The Pd-catalyzed intramolecular carbene C−H insertion of α-diazo-α-(methoxycarbonyl)acetamides to prepare oxindoles as well as β-lactams was studied. In order to identify what factors influence the selectivity of the processes, we explored how the reactions are a...

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Bibliographic Details
Main Authors: Daniel Solé, Ferran Pérez-Janer, Arianna Amenta, M.-Lluïsa Bennasar, Israel Fernández
Format: Article
Language:English
Published: MDPI AG 2019-09-01
Series:Molecules
Subjects:
palladium
diazo compounds
carbenes
oxindoles
β-lactams
density functional calculations
Online Access:https://www.mdpi.com/1420-3049/24/19/3551

Internet

https://www.mdpi.com/1420-3049/24/19/3551

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