Alteration of Mesopontine Cholinergic Function by the Lack of KCNQ4 Subunit

Alteration of Mesopontine Cholinergic Function by the Lack of KCNQ4 Subunit

The pedunculopontine nucleus (PPN), a structure known as a cholinergic member of the reticular activating system (RAS), is source and target of cholinergic neuromodulation and contributes to the regulation of the sleep–wakefulness cycle. The M-current is a voltage-gated potassium current modulated m...

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Bibliographic Details
Main Authors: T. Bayasgalan, S. Stupniki, A. Kovács, A. Csemer, P. Szentesi, K. Pocsai, L. Dionisio, G. Spitzmaul, B. Pál
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-07-01
Series:Frontiers in Cellular Neuroscience
Subjects:
KCNQ4 (Kv7.4)
M-current
pedunculopontine nucleus
neuronal synchronization
non-syndromic hearing loss (DFNA2)
potassium channels
Online Access:https://www.frontiersin.org/articles/10.3389/fncel.2021.707789/full

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https://www.frontiersin.org/articles/10.3389/fncel.2021.707789/full

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