The early pregnancy placenta foreshadows DNA methylation alterations of solid tumors

The early pregnancy placenta foreshadows DNA methylation alterations of solid tumors

The placenta relies on phenotypes that are characteristic of cancer to successfully implant the embryo in the uterus during early pregnancy. Notably, it has to invade its host tissues, promote angiogenesis—while surviving hypoxia—, and escape the immune system. Similarities in DNA methylation patter...

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Bibliographic Details
Main Authors: Akpéli V. Nordor, Djamel Nehar-Belaid, Sophie Richon, David Klatzmann, Dominique Bellet, Virginie Dangles-Marie, Thierry Fournier, Martin J. Aryee
Format: Article
Language:English
Published: Taylor & Francis Group 2017-09-01
Series:Epigenetics
Subjects:
cancer
dna methylation
epigenomics
epigenetics
hypomethylation
placenta
pregnancy
Online Access:http://dx.doi.org/10.1080/15592294.2017.1342912

Internet

http://dx.doi.org/10.1080/15592294.2017.1342912

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