A novel homozygous mutation in the PADI6 gene causes early embryo arrest

A novel homozygous mutation in the PADI6 gene causes early embryo arrest

Plain Language Summary Some infertile patients experience multiple in vitro fertilization/intracytoplasmic sperm injection (IVF/ICSI) failure owing to recurrent early embryo arrest. However, the underlying mechanisms remain largely unknown. Due to the development of whole-exome sequencing, early emb...

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Bibliographic Details
Main Authors: Xiaoxia Wang, Huimin Zhu, Yi He, Jun Zeng, Jing Zhao, Qiuping Xia, Lingqian Wu, Zhongyuan Yao, Yanping Li
Format: Article
Language:English
Published: BMC 2022-09-01
Series:Reproductive Health
Subjects:
Infertility
Early embryo arrest
Peptidylarginine deiminase type VI
Mutation
Subcortical maternal complex
Online Access:https://doi.org/10.1186/s12978-022-01495-7

Internet

https://doi.org/10.1186/s12978-022-01495-7

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