Bletilla striata Oligosaccharides Improve Ulcerative Colitis by Regulating Gut Microbiota and Intestinal Metabolites in Dextran Sulfate Sodium-Induced Mice

Bletilla striata Oligosaccharides Improve Ulcerative Colitis by Regulating Gut Microbiota and Intestinal Metabolites in Dextran Sulfate Sodium-Induced Mice

This study aimed to elucidate the mechanism of Bletilla striata oligosaccharides (BO) in the treatment of ulcerative colitis (UC). A UC mouse model was induced by 3% Dextran sodium sulfate (DSS), and BO (200 mg/kg/d) were administered for intervention. The results show that BO effectively inhibited...

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Bibliographic Details
Main Authors: Tianxiang Zhu, Baifei Hu, Cheng Ye, Haiming Hu, Mingzhu Yin, Zhigang Zhang, Shuiqing Li, Yanju Liu, Hongtao Liu
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-04-01
Series:Frontiers in Pharmacology
Subjects:
Bletilla striata oligosaccharides
ulcerative colitis
gut microbiota
intestinal metabolites
intestinal barrier
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2022.867525/full

Internet

https://www.frontiersin.org/articles/10.3389/fphar.2022.867525/full

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