AIFM1, negatively regulated by miR-145-5p, aggravates hypoxia-induced cardiomyocyte injury

Background: Hypoxia-induced apoptosis is linked to the pathogenesis of myocardial infarction. The role of apoptosis-inducing factor mitochondria associated 1 (AIFM1) in cardiomyocyte injury remains unclear. This study was aimed at probing into the role and the underlying regulatory mechanism of AIFM...

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Bibliographic Details
Main Authors: Wugang Zhou, Lv Ji, Xuqin Liu, Dan Tu, Ningning Shi, Wangmu Yangqu, Shi Chen, Pingjin Gao, Hong Zhu, Chengchao Ruan
Format: Article
Language:English
Published: Elsevier 2022-12-01
Series:Biomedical Journal
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2319417021001724