An optimized 3D-printed perfusion bioreactor for homogeneous cell seeding in bone substitute scaffolds for future chairside applications

An optimized 3D-printed perfusion bioreactor for homogeneous cell seeding in bone substitute scaffolds for future chairside applications

Abstract A clinical implementation of cell-based bone regeneration in combination with scaffold materials requires the development of efficient, controlled and reproducible seeding procedures and a tailor-made bioreactor design. A perfusion system for efficient, homogeneous, and rapid seeding with h...

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Bibliographic Details
Main Authors: Nadja Engel, Carsten Fechner, Annika Voges, Robert Ott, Jan Stenzel, Stefan Siewert, Carina Bergner, Valeria Khaimov, Jan Liese, Klaus-Peter Schmitz, Bernd Joachim Krause, Bernhard Frerich
Format: Article
Language:English
Published: Nature Portfolio 2021-11-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-021-01516-8

Internet

https://doi.org/10.1038/s41598-021-01516-8

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