Platelet Activation in Ovarian Cancer Ascites: Assessment of GPIIb/IIIa and PF4 in Small Extracellular Vesicles by Nano-Flow Cytometry Analysis

In ovarian cancer, ascites represent the microenvironment in which the platelets extravasate to play their role in the disease progression. We aimed to develop an assay to measure ascites’ platelet activation. We enriched small extracellular vesicles (EVs) (40–200 nm) from ascites of high-grade epit...

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Bibliographic Details
Main Authors: Barbara Bortot, Alessandro Mangogna, Ben Peacock, Rebecca Lees, Francesco Valle, Marco Brucale, Sara Tassinari, Federico Romano, Giuseppe Ricci, Stefania Biffi
Format: Article
Language:English
Published: MDPI AG 2022-08-01
Series:Cancers
Subjects:
Online Access:https://www.mdpi.com/2072-6694/14/17/4100