Identification of the Intron 22 and Intron 1 Inversions of the Factor VIII Gene in Iraqi Kurdish Patients With Hemophilia A

Identification of the Intron 22 and Intron 1 Inversions of the Factor VIII Gene in Iraqi Kurdish Patients With Hemophilia A

Hemophilia A (HA) is a severe coagulation disorder affecting 1 in 5000 to 10 000 male births. In severe cases, the most deleterious large DNA rearrangements are inversions of intron 22 (Inv22) and intron 1 (Inv1) of the factor VIII (FVIII) gene. These account for 40% to 50% and 1% to 5% of all causa...

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Bibliographic Details
Main Authors: Aveen M. Raouf Abdulqader MD, PhD, Ali Ibrahim Mohammed MD, FICMS, Shwan Rachid PhD, Peyman Ghoraishizadeh PhD, Sarwar Noori Mahmood MD, FICMS, FEBU
Format: Article
Language:English
Published: SAGE Publishing 2020-01-01
Series:Clinical and Applied Thrombosis/Hemostasis
Online Access:https://doi.org/10.1177/1076029619888293

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https://doi.org/10.1177/1076029619888293

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