Type 2 Diabetes Mellitus and Cardiovascular Disease: Genetic and Epigenetic Links

Type 2 Diabetes Mellitus and Cardiovascular Disease: Genetic and Epigenetic Links

Type 2 diabetes mellitus (DM) is a common metabolic disorder predisposing to diabetic cardiomyopathy and atherosclerotic cardiovascular disease (CVD), which could lead to heart failure through a variety of mechanisms, including myocardial infarction and chronic pressure overload. Pathogenetic mechan...

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Bibliographic Details
Main Authors: Salvatore De Rosa, Biagio Arcidiacono, Eusebio Chiefari, Antonio Brunetti, Ciro Indolfi, Daniela P. Foti
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-01-01
Series:Frontiers in Endocrinology
Subjects:
type 2 diabetes mellitus
cardiovascular disease
genetic polymorphisms
high-mobility group A1 variant
epigenetics
Online Access:http://journal.frontiersin.org/article/10.3389/fendo.2018.00002/full

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http://journal.frontiersin.org/article/10.3389/fendo.2018.00002/full

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