Multiplex Digital Quantification of β-Lactamase Genes in Antibiotic-Resistant Bacteria by Counting Gold Nanoparticle Labels on Silicon Microchips

Multiplex Digital Quantification of β-Lactamase Genes in Antibiotic-Resistant Bacteria by Counting Gold Nanoparticle Labels on Silicon Microchips

Digital quantification based on counting of individual molecules is a promising approach for different biomedical applications due to its enhanced sensitivity. Here, we present a method for the digital detection of nucleic acids (DNA and RNA) on silicon microchips based on the counting of gold nanop...

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Bibliographic Details
Main Authors: Galina V. Presnova, Denis E. Presnov, Anna A. Filippova, Ilia I. Tsiniaikin, Mariya M. Ulyashova, Maya Yu. Rubtsova
Format: Article
Language:English
Published: MDPI AG 2022-04-01
Series:Biosensors
Subjects:
high-sensitive digital detection
quantification
functionalized gold nanoparticles
microchips
β-lactamases
antibiotic-resistant bacteria
Online Access:https://www.mdpi.com/2079-6374/12/4/226

Internet

https://www.mdpi.com/2079-6374/12/4/226

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