Critical role of VHL/BICD2/STAT1 axis in crystal-associated kidney disease

Abstract Nephrolithiasis is highly prevalent and associated with the increased risk of kidney cancer. The tumor suppressor von Hippel-Lindau (VHL) is critical for renal cancer development, however, its role in kidney stone disease has not been fully elucidated until now. Here we reported VHL express...

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Bibliographic Details
Main Authors: Wenyan Hao, Hongxian Zhang, Peng Hong, Xin Zhang, Xuyang Zhao, Lulin Ma, Xiaoyan Qiu, Hao Ping, Dan Lu, Yuxin Yin
Format: Article
Language:English
Published: Nature Publishing Group 2023-10-01
Series:Cell Death and Disease
Online Access:https://doi.org/10.1038/s41419-023-06185-1