Metabolic labeling of the bacterial peptidoglycan by functionalized glucosamine

Summary: N-Acetylglucosamine (GlcNAc) is an essential monosaccharide required in almost all organisms. Fluorescent labeling of the peptidoglycan (PG) on N-acetylglucosamine has been poorly explored. Here, we report on the labeling of the PG with a bioorthogonal handle on the GlcNAc. We developed a f...

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Bibliographic Details
Main Authors: Yang Xu, Víctor M. Hernández-Rocamora, Joseph H. Lorent, Ruud Cox, Xiaoqi Wang, Xue Bao, Marjon Stel, Gaël Vos, Ramon M. van den Bos, Roland J. Pieters, Joe Gray, Waldemar Vollmer, Eefjan Breukink
Format: Article
Language:English
Published: Elsevier 2022-08-01
Series:iScience
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2589004222010252