Synergistic effects of influenza and 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) can be eliminated by the use of influenza therapeutics: experimental evidence for the multi-hit hypothesis

Abstract Central Nervous System inflammation has been implicated in neurodegenerative disorders including Parkinson’s disease (Ransohoff, Science 353: 777–783, 2016; Kannarkat et al. J. Parkinsons Dis. 3: 493–514, 2013). Here, we examined if the H1N1 influenza virus (Studahl et al. Drugs 73: 131–158...

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Bibliographic Details
Main Authors: Shankar Sadasivan, Bridgett Sharp, Stacey Schultz-Cherry, Richard Jay Smeyne
Format: Article
Language:English
Published: Nature Portfolio 2017-05-01
Series:npj Parkinson's Disease
Online Access:https://doi.org/10.1038/s41531-017-0019-z