Vincristine delays gastric emptying and gastrointestinal transit of liquid in awake rats

We evaluated the effects of vincristine on the gastrointestinal (GI) motility of awake rats and correlated them with the course of vincristine-induced peripheral neuropathy. Vincristine or saline was injected into the tail vein of male Wistar rats (180-250 g) on alternate days: 50 µg/kg (5 doses, N...

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Bibliographic Details
Main Authors: A.A. Peixoto Júnior, B.C.V Teles, E.F.B. Castro, A.A. Santos, G.R. de Oliveira, R.A. Ribeiro, F.H. Rola, F.A.A. Gondim
Format: Article
Language:English
Published: Associação Brasileira de Divulgação Científica 2009-06-01
Series:Brazilian Journal of Medical and Biological Research
Subjects:
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2009000600015