Metabolic engineering of Bacillus amyloliquefaciens for efficient production of α-glucosidase inhibitor1-deoxynojirimycin

Metabolic engineering of Bacillus amyloliquefaciens for efficient production of α-glucosidase inhibitor1-deoxynojirimycin

Owing to the feature of strong α-glucosidase inhibitory activity, 1-deoxynojirimycin (1-DNJ) has broad application prospects in areas of functional food, biomedicine, etc., and this research wants to construct an efficient strain for 1-DNJ production, basing on Bacillus amyloliquefaciens HZ-12. Firs...

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Bibliographic Details
Main Authors: Xujie Li, Meng Zhang, Yu Lu, Ningyang Wu, Jian'gang Chen, Zhixia Ji, Yangyang Zhan, Xin Ma, Junyong Chen, Dongbo Cai, Shouwen Chen
Format: Article
Language:English
Published: KeAi Communications Co., Ltd. 2023-09-01
Series:Synthetic and Systems Biotechnology
Subjects:
1-Deoxynojirimycin
Bacillus amyloliquefaciens
Metabolic engineering
Glucose transport pathway
Fructose 6-phosphate
1-DNJ synthetase Gene cluster
Online Access:http://www.sciencedirect.com/science/article/pii/S2405805X23000327

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http://www.sciencedirect.com/science/article/pii/S2405805X23000327

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