Inner nuclear protein Matrin-3 coordinates cell differentiation by stabilizing chromatin architecture

Interactions between chromatin and nuclear components and whether these interactions affect development is not well understood. Here the authors show inner nuclear protein Matrin-3 (Matr3) loss leads to accelerated erythroid maturation, and that Matr3 is involved in chromosomal structure organizatio...

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Bibliographic Details
Main Authors: Hye Ji Cha, Özgün Uyan, Yan Kai, Tianxin Liu, Qian Zhu, Zuzana Tothova, Giovanni A. Botten, Jian Xu, Guo-Cheng Yuan, Job Dekker, Stuart H. Orkin
Format: Article
Language:English
Published: Nature Portfolio 2021-10-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-021-26574-4