A New Class of β–Pyrrolidino-1,2,3-Triazole Derivatives as β-Adrenergic Receptor Inhibitors: Synthesis, Pharmacological, and Docking Studies

A New Class of β–Pyrrolidino-1,2,3-Triazole Derivatives as β-Adrenergic Receptor Inhibitors: Synthesis, Pharmacological, and Docking Studies

New 1,4-disubstituted β-pyrrolidino-1,2,3-triazoles were synthesized using a reusable copper-iodide-doped neutral alumina catalyst. Synthesis of diversely substituted triazoles and recyclability of CuI catalyst explains the broad scope of this protocol. The synthesized compounds were screen...

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Bibliographic Details
Main Authors: Kaliyappan Easwaramoorthi, Jeya A. Rajendran, Kella Chennakesava Rao, Chandrasekar Balachandran, Yuvaraj Arun, Sakkarapalayam M. Mahalingam, Natarajan Arumugam, Abdulrahman I. Almansour, Raju Suresh Kumar, Dhaifallah M. Al-thamili, Shin Aoki
Format: Article
Language:English
Published: MDPI AG 2019-09-01
Series:Molecules
Subjects:
β–pyrrolidino-1,2,3-triazole
β-adrenoceptors
antimicrobial activity
anticancer activity
docking studies
Online Access:https://www.mdpi.com/1420-3049/24/19/3501

Internet

https://www.mdpi.com/1420-3049/24/19/3501

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