Rab2 drives axonal transport of dense core vesicles and lysosomal organelles

Rab2 drives axonal transport of dense core vesicles and lysosomal organelles

Summary: Fast axonal transport of neuropeptide-containing dense core vesicles (DCVs), endolysosomal organelles, and presynaptic components is critical for maintaining neuronal functionality. How the transport of DCVs is orchestrated remains an important unresolved question. The small GTPase Rab2 med...

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Bibliographic Details
Main Authors: Viktor Karlovich Lund, Matthew Domenic Lycas, Anders Schack, Rita Chan Andersen, Ulrik Gether, Ole Kjaerulff
Format: Article
Language:English
Published: Elsevier 2021-04-01
Series:Cell Reports
Subjects:
Rab2
Arl8
dense core vesicles
axonal transport
membrane trafficking
endosomes
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124721002874

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http://www.sciencedirect.com/science/article/pii/S2211124721002874

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