Phosphorylation in liquid sulfur dioxide under prebiotically plausible conditions

Organophosphates are essential to facilitate information storage and energy transfer in living organisms, but their prebiotic origins remain unknown. Here, the authors report a liquid sulfur dioxide-mediated phosphorylation of nucleosides from phosphorous acid in a single reaction step at room tempe...

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Bibliographic Details
Main Authors: Constanze Sydow, Christiane Seiband, Alexander F. Siegle, Oliver Trapp
Format: Article
Language:English
Published: Nature Portfolio 2022-11-01
Series:Communications Chemistry
Online Access:https://doi.org/10.1038/s42004-022-00761-w