Synthesis and antitumor activities of diaqua platinum (II) complexes with carboxylates(二水羧酸根合铂(II)混配配合物的合成及其抗肿瘤活性)
首次合成两种二水羧酸根合铂类配合物[Pt(II)(H2O)2(OOC—CH2NH2)2](1)和[Pt(II)(H2O)2(OOC—CH=CHCOO)](2).用元素分析、摩尔电导、差热热重分析、红外光谱、紫外光谱和核磁共振氢谱对其进行了表征.体外抗肿瘤活性表明，两种配合物对所试的肿瘤细胞表现出较低的活性，在10 µM浓度下配合物对人膀胱癌细胞EJ的增殖抑制率分别为25.77% 和28.27%....
| Main Authors: | , , , , |
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| Format: | Article |
| Language: | zho |
| Published: |
Zhejiang University Press
2005-03-01
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| Series: | Zhejiang Daxue xuebao. Lixue ban |
| Subjects: | |
| Online Access: | https://doi.org/zjup/1008-9497.2005.32.2.189-193 |