Androgen increases klotho expression via the androgen receptor-mediated pathway to induce GCs apoptosis

Androgen increases klotho expression via the androgen receptor-mediated pathway to induce GCs apoptosis

Abstract Background Many epidemiological studies have shown that anovulatory polycystic ovary syndrome (PCOS) is accompanied by hyperandrogenism. However, the exact mechanism of hyperandrogen-induced anovulation remains to be elucidated. In this study, we aimed to investigate the potential mechanism...

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Bibliographic Details
Main Authors: Xin Zeng, Qiaoqing Zhong, Ming Li, Yating Liu, Shuanglian long, Yuanjie Xie, Zhongcheng Mo
Format: Article
Language:English
Published: BMC 2023-01-01
Series:Journal of Ovarian Research
Subjects:
Testosterone propionate
Androgen receptor
Klotho
Polycystic ovarian syndrome
Online Access:https://doi.org/10.1186/s13048-022-01087-w

Internet

https://doi.org/10.1186/s13048-022-01087-w

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