Involvement of <i>hpap2</i> and <i>dgkA</i> Genes in Colistin Resistance Mediated by <i>mcr</i> Determinants

Involvement of <i>hpap2</i> and <i>dgkA</i> Genes in Colistin Resistance Mediated by <i>mcr</i> Determinants

Plasmid-mediated colistin resistance (<i>mcr</i>) determinants are challenging the efficacy of polymyxins against Gram-negative pathogens. Among 10 <i>mcr</i> genes described so far, the major determinants <i>mcr-1</i> and <i>mcr-3</i> are found closel...

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Bibliographic Details
Main Authors: Alejandro Gallardo, María Ugarte-Ruiz, Marta Hernández, Pedro Miguela-Villoldo, David Rodríguez-Lázaro, Lucas Domínguez, Alberto Quesada
Format: Article
Language:English
Published: MDPI AG 2020-08-01
Series:Antibiotics
Subjects:
colistin (polymyxin) resistance
<i>mcr-1</i>
<i>mcr-3</i>
<i>pap2</i>
<i>dagK</i>
lipid A (LPS)
Online Access:https://www.mdpi.com/2079-6382/9/9/531

Internet

https://www.mdpi.com/2079-6382/9/9/531

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