Combining angiotensin receptor blockade and enzyme replacement therapy for vascular disease in mucopolysaccharidosis type I

Combining angiotensin receptor blockade and enzyme replacement therapy for vascular disease in mucopolysaccharidosis type I

Vascular involvement in the genetic disorder mucopolysaccharidosis type I (MPS I) has features of atherosclerotic disease near branch points of arterial vasculature, such as intimal thickening with disruption of the internal elastic lamina, and proliferation of macrophages and myofibroblasts. Inflam...

Full description

Bibliographic Details
Main Authors: Sarah C. Hurt, Moin U. Vera, Steven Q. Le, Shih-hsin Kan, Quang Bui, Patricia I. Dickson
Format: Article
Language:English
Published: Elsevier 2024-03-01
Series:Molecular Genetics and Metabolism Reports
Subjects:
Lysosomal storage disease
Hurler
Scheie
Hurler-Scheie
Losartan
Alpha-L-iduronidase
Online Access:http://www.sciencedirect.com/science/article/pii/S2214426923000824

Internet

http://www.sciencedirect.com/science/article/pii/S2214426923000824

Similar Items