Droplet Digital PCR as a Molecular Tool for the Detection of the EGFR T790M Mutation in NSCLC Patients with the EGFR Activating Mutations

Droplet Digital PCR as a Molecular Tool for the Detection of the EGFR T790M Mutation in NSCLC Patients with the EGFR Activating Mutations

Almost 50% of NSCLC patients who initially show a successful response to tyrosine kinase inhibitors targeted therapy (TKI therapy) eventually develop acquired EGFR T790M mutation. The T790M secondary mutation can cause resistance to the targeted therapy and disease relapse. Since this mutation can b...

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Bibliographic Details
Main Authors: Durgut S, Salihefendić L, Pećar D, Čeko I, Mulahuseinović N, Izmirlija M, Konjhodžić R
Format: Article
Language:English
Published: Sciendo 2024-03-01
Series:Balkan Journal of Medical Genetics
Subjects:
ddpcr
liquid biopsy
nsclc patients
t790m
Online Access:https://doi.org/10.2478/bjmg-2023-0020

Internet

https://doi.org/10.2478/bjmg-2023-0020

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