Genome-scale CRISPR screens identify host factors that promote human coronavirus infection

Abstract Background The COVID-19 pandemic has resulted in 275 million infections and 5.4 million deaths as of December 2021. While effective vaccines are being administered globally, there is still a great need for antiviral therapies as antigenically novel SARS-CoV-2 variants continue to emerge acr...

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Bibliographic Details
Main Authors: Marco Grodzki, Andrew P. Bluhm, Moritz Schaefer, Abderrahmane Tagmount, Max Russo, Amin Sobh, Roya Rafiee, Chris D. Vulpe, Stephanie M. Karst, Michael H. Norris
Format: Article
Language:English
Published: BMC 2022-01-01
Series:Genome Medicine
Online Access:https://doi.org/10.1186/s13073-022-01013-1